AntiInfectiveMeds
Since 2010
| Quantity | Price per tablet | You save | Total price | |
|---|---|---|---|---|
| 10 | A$10.79 | - | A$107.92 | |
| 20 | A$6.08 | A$94.24 | A$121.60 | |
| 30 | A$4.46 | A$190.00 | A$133.76 | |
| 60 | A$2.48 | A$498.56 | A$148.96 | |
| 90 | A$1.79 | A$810.16 | A$161.12 | |
| 120 | A$1.46 | A$1,120.24 | A$174.80 | |
| 180 | A$1.04 | A$1,755.60 | A$186.96 | |
| 270 | A$0.74 | A$2,713.20 | A$200.64 | |
| 360 | A$0.63 | A$3,657.12 | A$228.00 |
| Quantity | Price per tablet | You save | Total price | |
|---|---|---|---|---|
| 10 | A$9.88 | - | A$98.80 | |
| 20 | A$5.47 | A$88.16 | A$109.44 | |
| 30 | A$4.10 | A$173.28 | A$123.12 | |
| 60 | A$2.23 | A$459.04 | A$133.76 | |
| 90 | A$1.59 | A$746.32 | A$142.88 | |
| 120 | A$1.28 | A$1,032.08 | A$153.52 | |
| 180 | A$1.10 | A$1,580.80 | A$197.60 | |
| 270 | A$0.90 | A$2,425.92 | A$241.68 | |
| 360 | A$0.85 | A$3,249.76 | A$307.04 |
Your order is carefully packed and ships within 24 hours. Here is what a typical package looks like.
Sized like a regular personal letter (approximately 24x11x0.7 cm), with no indication of what is inside.
| Delivery Method | Estimated delivery |
|---|---|
| Express Free for orders over A$456.00 | Estimated delivery to Australia: 4-7 days |
| Standard Free for orders over A$304.00 | Estimated delivery to Australia: 14-21 days |
Ampicillin tablets are a penicillin-class (beta-lactam) antibiotic used to treat certain bacterial infections when the bacteria are susceptible. In Australia, they should only be used on the advice of a prescriber and exactly as directed. Antibiotics do not work for colds, flu or other viral illnesses.
Ampicillin is a beta-lactam antibiotic. It kills bacteria and works in a similar way to penicillin G (benzylpenicillin). As an aminopenicillin with an amino side chain attached to the basic penicillin structure, ampicillin can better penetrate the outer membrane of some Gram-negative bacteria and has a broader spectrum of activity.
Ampicillin is similar to benzylpenicillin in its action against Gram-positive organisms, including Streptococcus pneumoniae and other streptococci, but, with the possible exception of activity against Enterococcus faecalis, it may be slightly less potent than benzylpenicillin. Listeria monocytogenes is generally susceptible. The Gram-negative cocci Moraxella catarrhalis (Branhamella catarrhalis), Neisseria gonorrhoeae, and N. meningitidis may be susceptible, depending on local resistance patterns.
Ampicillin is more active than benzylpenicillin against some Gram-negative bacilli, including Haemophilus influenzae and Enterobacteriaceae such as Escherichia coli, Proteus mirabilis, Salmonella and Shigella spp. It is inactive against Pseudomonas aeruginosa.
Ampicillin also has activity similar to benzylpenicillin against other organisms, including many anaerobes and Actinomyces spp.
Activity with other antimicrobials. Synergy has been shown between ampicillin and aminoglycosides against some organisms, including enterococci. Effects ranging from synergy to antagonism have been reported between ampicillin and other beta-lactams, bacteriostatic drugs such as chloramphenicol, and rifampicin.
Resistance. Like benzylpenicillin, ampicillin is inactivated by beta-lactamases, although other mechanisms may be responsible for resistance in some species. Resistance rates vary by region; many strains of staphylococci and some Gram-negative organisms may be resistant.
Ampicillin is relatively resistant to inactivation by gastric acid and is moderately well absorbed from the gastrointestinal tract after oral doses. Food can interfere with ampicillin absorption, so doses are often taken on an empty stomach (e.g. at least 30 minutes before meals). Peak plasma concentrations are reached in about 1 to 2 hours; after a 500-mg oral dose, peak levels have been reported to range from 3 to 6 mcg/mL.
Ampicillin is widely distributed and crosses the placenta; small amounts pass into breast milk. There is little diffusion into the CSF except when the meninges are inflamed. About 20% is bound to plasma proteins, and the plasma half-life is about 1 to 1.5 hours, but this may be increased in neonates, older adults and patients with renal impairment.
Ampicillin is metabolised to some extent to penicilloic acid and is eliminated mainly by the kidneys. Renal clearance occurs partly by glomerular filtration and partly by tubular secretion, and is reduced by probenecid.
Ampicillin tablets are used to treat a range of infections caused by susceptible organisms. Common examples include certain respiratory tract infections, urinary tract infections, gastrointestinal infections, and skin and soft tissue infections when the causative bacteria are known or likely to be susceptible. Whenever possible, in Australian clinical practice, treatment should be guided by culture and susceptibility results.
| Feature | Ampicillin (tablets) | Amoxicillin |
|---|---|---|
| Drug class | Aminopenicillin (beta-lactam) | Aminopenicillin (beta-lactam) |
| Absorption and food | Food can reduce absorption; often taken on an empty stomach (e.g. at least 30 minutes before meals) | Generally better oral absorption; can usually be taken with or without food (follow your product label/prescriber's advice) |
| Dosing convenience | Often requires more frequent dosing (commonly every 6 hours, depending on the infection) | Often less frequent dosing (commonly every 8-12 hours, depending on the infection) |
| Penicillin allergy | Both are penicillins. Avoid them if you have a serious penicillin allergy (e.g. anaphylaxis). Tell your clinician about any past reactions. | |
Take ampicillin tablets exactly as prescribed by your Australian doctor. Because food can reduce absorption, it is often taken on an empty stomach (e.g. at least 30 minutes before meals). Finish the full course unless your prescriber tells you to stop.
Common side effects may include diarrhoea, nausea, vomiting and skin rash. Get urgent medical help for signs of a severe allergic reaction (e.g. swelling of the face or throat, trouble breathing), severe skin reactions, or severe or persistent diarrhoea (which can be a sign of Clostridioides difficile-associated diarrhoea).
Pregnancy: animal studies with penicillins have not shown harm to the fetus, but there are no adequate, well-controlled studies in pregnant women. Use during pregnancy only if clearly needed and as prescribed by an Australian doctor.
Breastfeeding: ampicillin-class antibiotics are excreted in breast milk and may cause sensitisation in the infant; use with caution and contact a clinician if the baby develops rash, diarrhoea or thrush.
Dose adjustment may be needed in renal impairment. Follow your prescriber's instructions if you have kidney disease or are receiving dialysis.
Store at 20°C to 25°C (68°F to 77°F). Keep the container tightly closed and out of the reach of children.
My ampicillin parcel was left outside at my Ballarat home on a very hot day. What should I check before taking the capsules?
Check that the pack is intact, dry and within its expiry date, and that the capsules have no unusual damage or change; keep them protected from moisture and store them at 20°C to 25°C. Do not use capsules if the packaging or capsules appear compromised.
I'm in Coffs Harbour and am concerned about the trip in the post. How are ampicillin capsules protected during transport?
Capsules are a solid oral dosage form and can normally travel by post when correctly packed and handled. On arrival, check that the package is dry and intact, then store the capsules in a tightly closed container at 20°C to 25°C, protected from moisture. We cannot promise temperature-controlled transport.
I take atenolol every morning for blood pressure. Is there anything I need to know before starting ampicillin?
Ampicillin may reduce the amount of atenolol absorbed, which could affect its blood-pressure-lowering effect. Tell the prescriber or pharmacist managing your treatment so they can advise on timing and whether any monitoring is needed; do not change either medicine yourself.
| Active ingredient | Ampicillin |
|---|---|
| Drug class | Penicillin antibiotic |
| Dosage form | Capsule |
| Available strengths | 250 mg, 500 mg |
| Route | Oral |
| Storage | Store capsules at 20°C to 25°C in a tightly closed container, protected from moisture. |
| ATC code | J01CA01 |
This product has 5 ratings, but only 3 written reviews so far. Share your experience and help other customers.
I'd order Ampicillin again.
Really pleased with the product.
The parcel had plain outer packaging, so the contents weren't obvious around others.
