AntiInfectiveMeds
Since 2010
| Quantity | Price per tablet | You save | Total price | |
|---|---|---|---|---|
| 60 | A$2.18 | - | A$130.72 | |
| 90 | A$1.99 | A$16.72 | A$179.36 | |
| 120 | A$1.89 | A$34.96 | A$226.48 | |
| 180 | A$1.80 | A$68.40 | A$323.76 | |
| 270 | A$1.73 | A$121.60 | A$466.64 | |
| 360 | A$1.71 | A$170.24 | A$614.08 |
Your order is carefully packed and ships within 24 hours. Here is what a typical package looks like.
Sized like a regular personal letter (approximately 24x11x0.7 cm), with no indication of what is inside.
| Delivery Method | Estimated delivery |
|---|---|
| Express Free for orders over A$456.00 | Estimated delivery to Australia: 4-7 days |
| Standard Free for orders over A$304.00 | Estimated delivery to Australia: 14-21 days |
| Country | Brand Names |
|---|---|
| Australia | Biaxsig Rulide |
Roxithromycin is a macrolide antibiotic used in some countries, including Australia, to treat bacterial infections caused by susceptible organisms. It is most commonly used for respiratory tract infections and some skin and soft tissue infections. It is an oral, prescription-only medicine, typically prescribed in Australian clinical practice when a doctor decides it is appropriate.
Australian note: Roxithromycin is available in Australia, but it should only be used under the guidance of a registered healthcare professional.
Roxithromycin may be prescribed for bacterial infections caused by susceptible organisms, including some upper and lower respiratory tract infections and some skin and soft tissue infections. It does not work for viral illnesses such as colds or flu.
Where it is approved, roxithromycin is usually taken by mouth once or twice daily, often at least 15 minutes before meals, as food can reduce absorption. Follow your prescriber's instructions and complete the full course unless you are told otherwise.
| Comparison | Roxithromycin | Amoxicillin | Azithromycin | Erythromycin |
|---|---|---|---|---|
| Drug class | Macrolide | Penicillin (beta-lactam) | Macrolide (azalide) | Macrolide |
| Typical role | An alternative option in some countries for susceptible respiratory or skin infections | A common first-line option for many ENT and respiratory infections, when appropriate | Often used for some respiratory infections and certain atypical pathogens, when appropriate | An older macrolide; still used, but often limited by GI side effects and interactions |
| Penicillin allergy | May be an alternative for some people with penicillin allergy, depending on clinical judgement | Not suitable in true immediate-type penicillin allergy | May be an alternative for some people with penicillin allergy, depending on clinical judgement | May be an alternative for some people with penicillin allergy, depending on clinical judgement |
| Food effect | Absorption can be reduced by food; it is often taken before meals | Usually can be taken with or without food, depending on the product | Depends on the formulation; many can be taken with or without food | Depends on the salt or formulation; some are affected by food |
| Common side effects | GI upset (nausea, abdominal pain, diarrhoea), headache, rash | GI upset, rash; diarrhoea can occur | GI upset; diarrhoea; often less nausea than erythromycin | GI upset is common; nausea and abdominal cramps are frequent |
| QT/arrhythmia risk | Macrolide class warning: QT prolongation can occur in rare cases | Not a typical QT-prolonging antibiotic | Macrolide class warning: QT prolongation can occur in rare cases | Macrolide class warning: QT prolongation can occur in rare cases |
| Drug interaction potential | Can interact with some medicines (see below); use caution with anticoagulants | Fewer CYP-related interactions than macrolides | Generally fewer CYP3A interactions than erythromycin/clarithromycin | Higher interaction burden (CYP-related) than many alternatives |
| Scenario (simplified) | Often considered | Notes |
|---|---|---|
| Typical bacterial ENT or respiratory infection where a beta-lactam is appropriate | Amoxicillin | A common first-line choice in many guidelines and markets; this depends on the diagnosis and local resistance patterns. |
| Suspected "atypical" respiratory pathogens, or when a macrolide-type option is needed | Azithromycin | Often preferred within the macrolide class because of convenient dosing and generally fewer CYP3A interactions than erythromycin. |
| Need for a macrolide alternative where available locally | Roxithromycin | Used in some countries; take local product information into account |
| Macrolide needed but newer alternatives are not suitable or available | Erythromycin | Effective in some settings, but GI side effects and interaction burden can limit its use. |
| When to be extra cautious with macrolides | Roxithromycin / Azithromycin / Erythromycin | Use caution with known QT prolongation, electrolyte abnormalities, or other QT-prolonging medicines. |
Roxithromycin is a macrolide antibiotic. It binds to the 50S ribosomal subunit and blocks bacterial protein synthesis.
Common side effects include nausea, abdominal pain, diarrhoea, headache and skin rash.
Stop taking the medicine and seek urgent medical care if you develop signs of a serious allergic reaction, such as swelling of the face, lips or tongue, trouble breathing, severe skin reactions such as a blistering or peeling rash, severe or persistent diarrhoea, or symptoms of liver injury such as dark urine, yellowing of the skin or eyes, or severe fatigue.
Tell your Australian clinician or pharmacist about all medicines and supplements you take. Important interactions may include:
Roxithromycin has an absolute bioavailability of approximately 50%. Peak concentrations usually occur about 1-2 hours after a dose. Food can reduce absorption. It is highly protein-bound and distributed into tissues; small amounts may be found in breast milk. Elimination occurs by multiple routes, including faecal and urinary excretion, with a reported half-life of around 12 hours in healthy adults. The half-life may be prolonged in hepatic or renal impairment.
Some studies have looked at macrolides, including roxithromycin, for conditions such as gingival overgrowth or cardiovascular prevention. These are not standard labelled indications.
Store below 25°C (77°F) in a cool, dry place. Protect from light and moisture. Keep out of reach of children.
My Roxithromycin has arrived in Mackay. Where do I find the batch number and expiry date on the pack?
The batch or lot number and expiry date are normally printed on the outer carton and often on the blister strip as well. Check that the active ingredient, 150 mg strength, dosage form, batch details and expiry date are legible before use.
My son is 11 and weighs 35 kg. Is the 150 mg Roxithromycin film-coated tablet suitable for children his size?
The 150 mg film-coated tablet is generally intended for children weighing more than 40 kg. A child who weighs 35 kg needs an age- and weight-appropriate treatment decision and formulation rather than this fixed-strength tablet.
| Active ingredient | Roxithromycin |
|---|---|
| Drug class | Macrolide antibiotic |
| Dosage form | Film-coated tablet |
| Available strengths | 150 mg |
| Route of administration | Oral |
| Storage | Store below 25°C in a dry place, protected from moisture and light. |
| ATC code | J01FA06 |
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Good quality overall.
A solid product overall.
Customs cleared the parcel without questions or extra trouble.
