Zyvox (Linezolid)

Zyvox
4.116 ratingsReviews
Generic:
Linezolid
Indications:
infections
Analogs:
Vancomycin Daptomycin Tedizolid Ceftaroline Tigecycline Dalbavancin Oritavancin Clindamycin Linezolid Sivextro Cubicin Teflaro Dalvance Orbactiv Tygacil Bactrim Synercid
In stock: 14 packs
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Zyvox 600 mg

Quantity Price per tablet You save Total price
30 A$9.22 - A$276.64
60 A$8.74 A$28.88 A$524.40

Manufacturers

Accord HealthcareCipla LimitedLaboratorios NormonPfizerPfizer CanadaratiopharmSandoz

Payment & Delivery

Package Example

Your order is carefully packed and ships within 24 hours. Here is what a typical package looks like.

Sized like a regular personal letter (approximately 24x11x0.7 cm), with no indication of what is inside.

Front View
Front View
Side View
Side View
Back View
Back View
Delivery Times
Delivery MethodEstimated delivery
Express Free for orders over A$456.00Estimated delivery to Australia: 4-7 days
Standard Free for orders over A$304.00Estimated delivery to Australia: 14-21 days
EMSAustralia Post
Payment Methods
VisaMastercardBitcoin, USDTApple PayGoogle PayEftposAfterpayZippayKlarnaPayPal

Discount Coupons

  • Australia Day - 26 January 2026 10% AUSDAY10
  • Labour Day - 2 March 2026 6% LABOUR6
  • ANZAC Day - 25 April 2026 8% ANZAC8
  • King's Birthday - 8 June 2026 7% KING7
  • Boxing Day - 26 December 2026 12% BOXING12

Brand Names

Also known as (by country):
CountryBrand Names
Australia
Linezolid Sandoz

FAQ

Yes, linezolid is a Schedule 4 Prescription Only Medicine and requires a prescription when bought from an Australian pharmacy. Our store policy allows you to order Zyvox without a prescription and have it sent by mail.

Take the missed dose when you remember unless it is nearly time for the next dose. If it is nearly time, skip the missed dose and return to the usual schedule. Do not take two doses together or an extra dose to make up for one missed.

Do not keep leftover linezolid for a future illness or give it to someone else. Return unused tablets to a pharmacy for safe disposal where possible. The originally prescribed treatment should not be extended using leftover tablets without clinical review.

The manufacturer of the supplied product may vary. The manufacturer's name is shown on the product packaging.

Do not take the tablets if the label shows a strength other than 600 mg. Keep the packaging and compare the active ingredient, strength, dosage form, manufacturer, lot number and expiry date with your order details, then request an order review.

Store the tablets at 25°C; temperature excursions between 15°C and 30°C are permitted. Protect them from light and moisture, and keep bottles tightly closed. Keep the medicine out of reach of children.

Linezolid 600 mg film-coated tablets are taken by mouth and may be taken with or without food. For many adult infections, the usual regimen is 600 mg every 12 hours, but the treatment length and exact regimen depend on the infection and the prescriber's plan. Swallow the tablet with water and take doses at evenly spaced times.

Linezolid is an oxazolidinone antibiotic used for susceptible Gram-positive bacterial infections. Established uses include certain hospital-acquired and community-acquired pneumonias, skin and soft-tissue infections, and infections caused by vancomycin-resistant Enterococcus faecium. It is not a treatment for viral infections and is not generally used for Gram-negative infections.

Common effects include nausea, diarrhoea, vomiting, headache, altered taste and dizziness. More serious effects can include low blood cell counts, severe or persistent diarrhoea, visual changes, nerve symptoms, lactic acidosis and serotonin syndrome when combined with certain medicines. Seek urgent medical care for severe allergic symptoms, confusion, high fever, muscle stiffness or sudden vision changes.

During pregnancy, linezolid should be used only after a clinician has weighed the expected benefit against potential fetal risk; it is classified as Pregnancy Category B3 in Australia. During breastfeeding, caution is advised because linezolid can pass into milk. The decision should consider the importance of treatment and monitoring the infant for diarrhoea, vomiting or oral thrush.

Description

Note: Images in the description are provided for informational purposes and may differ from the actual appearance of the product. Please refer to the product name, strength, active ingredients, and dosage form.

Zyvox (linezolid) is an oxazolidinone antibiotic used to treat certain serious infections caused by susceptible Gram-positive bacteria.

Drug class

Linezolid belongs to the oxazolidinone class of antibiotics.

How it works

Linezolid blocks bacterial protein synthesis at an early stage by preventing the formation of the 70S initiation complex.

What Zyvox tablets treat (and what they do not)

Disease / condition (A-Z) Zyvox tablets
Community-acquired pneumonia (CAP) +
Complicated skin and skin structure infections +
Diabetic foot infection (without concomitant osteomyelitis) +
Gonorrhoea -
Gram-negative infections (e.g., E. coli, Pseudomonas) -
Hospital-acquired / nosocomial pneumonia (HAP) +
Osteomyelitis -
Pressure injuries (pressure ulcers) -
Uncomplicated skin and skin structure infections +
Urinary tract infection (UTI) -
VRE (Enterococcus faecium) infection, including cases with concurrent bacteraemia +
Viral infections (flu/common cold) -
Yeast or other fungal infections -

Limitations of use (Australia): Zyvox is not indicated for the treatment of Gram-negative infections. If a Gram-negative pathogen is suspected or confirmed, appropriate treatment should be started.

Indications (US labelling)

Zyvox tablets are used for certain infections caused by susceptible Gram-positive bacteria, including pneumonia (hospital-acquired and community-acquired), skin and skin structure infections (complicated and uncomplicated), and vancomycin-resistant Enterococcus faecium (VRE) infections, including cases with concurrent bacteraemia.

Tablet strength

  • Tablet: 600 mg (film-coated).

Can you split the tablet?

Zyvox 600 mg tablets are film-coated and are not described as scored tablets in Australian product information. For this reason, splitting or crushing is generally not recommended unless a clinician specifically advises it.

Zyvox

Why is Zyvox expensive? Are there alternatives?

Cost can be influenced by brand pricing, manufacturing and supply chain factors, and market conditions. Depending on the infection and culture/susceptibility results, clinicians may choose alternatives. TGA-registered generic linezolid tablets are available in Australia and may cost less than the brand in some cases.

What medicines is it used with?

Zyvox may be used on its own for confirmed susceptible Gram-positive infections. If an infection is mixed or a Gram-negative pathogen is suspected, clinicians may prescribe Zyvox together with other antibiotics that cover Gram-negative organisms and, when needed, anaerobes. The exact combination depends on the site of infection, its severity, and local resistance patterns.

Clinical studies in Australia
Clinical studies in Australia on linezolid have mainly looked at its use in serious Gram-positive infections, particularly methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci, often in hospital settings. These studies generally found linezolid to be an effective alternative to glycopeptides, with strong oral bioavailability supporting step-down therapy and reducing the need for prolonged intravenous treatment. Australian reports have also highlighted the need for safety monitoring, especially for thrombocytopenia, anaemia, peripheral or optic neuropathy with prolonged use, and drug interactions related to monoamine oxidase inhibition.

Drug interactions

Linezolid is a reversible, non-selective MAO inhibitor (MAOI). It can interact with adrenergic drugs, which may raise blood pressure, and serotonergic drugs, which may increase the risk of serotonin syndrome. Tell your Australian clinician about all prescription, over-the-counter, and herbal products you use.

Linezolid has been used in Australia since 2001.

Contraindications

Contraindication What it means
Hypersensitivity to linezolid (or any component of the product) Do not use if you have a known serious allergy to linezolid or any of the product ingredients.
Use with MAO inhibitors (or within 2 weeks of stopping an MAOI) Do not use with MAOIs (e.g., phenelzine, isocarboxazid, selegiline) or within 2 weeks of stopping them because of the risk of interactions.

Tyramine (food interaction)

Because linezolid has MAOI activity, avoid consuming large amounts of tyramine-rich foods and drinks during treatment. Examples include aged cheeses, cured, aged or improperly stored meats, fermented foods (including some soy and yeast products), and certain alcoholic drinks (such as some beers and red wine). Seek medical help if you develop a severe headache, flushing, or a marked rise in blood pressure.

Side effects and key precautions

Common side effects include diarrhoea, nausea, vomiting, and headache.

Important warnings and precautions include myelosuppression (including thrombocytopenia; full blood counts are commonly monitored weekly), peripheral and optic neuropathy (reported mainly with treatment longer than 28 days), lactic acidosis, seizures, and C. difficile-associated diarrhoea. Report unusual bruising or bleeding, severe or persistent diarrhoea, or new visual symptoms straight away, including blurred vision or changes in visual acuity or colour vision.

Australian doctors advise confirming that linezolid is appropriate for your condition before use.

Storage

Store at 25°C. Excursions between 15°C and 30°C are permitted.

Medically reviewed by
Donna Brettler
BPharm, MPH - Pharmacologist and medical writer
Updated 11 August 2026

Customer questions

Asked by Jack F, Newcastle, Australia

I'm in Newcastle and am concerned about the medicine travelling in warm weather. Are these linezolid tablets suitable for ordinary postal transport?

Answered by Support team

Linezolid 600 mg is supplied as film-coated tablets, a solid oral form that can normally travel by post when packed and handled appropriately. The tablets should be protected from light and moisture and stored at 25°C, with permitted excursions from 15°C to 30°C; inspect the package, seal and tablets on arrival before use.

Asked by Evie J, Bendigo, Australia

I've been prescribed linezolid for three weeks and have had low blood counts before. Will I need blood tests during the course?

Answered by Support team
Medical reviewed by Donna Brettler

Weekly full blood counts are generally recommended during linezolid treatment because it can cause reversible myelosuppression, particularly with courses longer than two weeks or in people at higher risk. Your prescriber can arrange the appropriate monitoring for your treatment.

Product specifications

Active ingredientLinezolid
Drug classOxazolidinone antibiotic
Dosage formFilm-coated tablet
Available strengths600 mg
RouteOral
StorageStore at 25°C; excursions permitted to 15°C to 30°C. Protect from light and keep bottles tightly closed to protect from moisture.
ATC codeJ01XX08

Regulatory information

Approval statusLinezolid is registered and approved for clinical human use in Australia.
Prescription requirementsLinezolid film-coated tablets are classified as Schedule 4 (Prescription Only Medicine) in Australia and require an authorized doctor's prescription.

More information