AntiInfectiveMeds
Since 2010
| Quantity | Price per tablet | You save | Total price | |
|---|---|---|---|---|
| 30 | A$4.00 | - | A$120.08 | |
| 60 | A$3.07 | A$56.24 | A$183.92 | |
| 90 | A$2.70 | A$117.04 | A$243.20 | |
| 120 | A$2.57 | A$171.76 | A$308.56 | |
| 180 | A$2.41 | A$287.28 | A$433.20 | |
| 270 | A$2.30 | A$460.56 | A$620.16 | |
| 360 | A$2.26 | A$626.24 | A$814.72 |
Your order is carefully packed and ships within 24 hours. Here is what a typical package looks like.
Sized like a regular personal letter (approximately 24x11x0.7 cm), with no indication of what is inside.
| Delivery Method | Estimated delivery |
|---|---|
| Express Free for orders over A$456.00 | Estimated delivery to Australia: 4-7 days |
| Standard Free for orders over A$304.00 | Estimated delivery to Australia: 14-21 days |
Ketoconazole tablets (oral ketoconazole) are used to treat certain serious fungal infections that affect the body only when other effective antifungal treatment is not available or cannot be tolerated and when the potential benefits are considered to outweigh the potential risks.
According to Australian product information, ketoconazole tablets are indicated for the treatment of the following systemic fungal infections in patients who have not responded to, or cannot tolerate, other therapies: blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis (chromoblastomycosis), and paracoccidioidomycosis.
This medicine should not be used as initial treatment for severe, life-threatening infections. Because levels in the cerebrospinal fluid (CSF) are unpredictable after oral use, ketoconazole tablets should not be used to treat fungal infections of the central nervous system (CNS), including fungal meningitis. Close follow-up during and after treatment is recommended.
Oral ketoconazole is used to treat blastomycosis caused by Blastomyces dermatitidis in selected patients when other effective antifungal treatment is not available or cannot be tolerated. Severe disease, including suspected CNS involvement, generally needs specialist care and alternative systemic treatment.
Oral ketoconazole has been used for chromomycosis (chromoblastomycosis) caused by Phialophora spp. Response can vary, and treatment should be tailored by a clinician experienced in systemic fungal infections.
Oral ketoconazole is used for mild to moderate coccidioidomycosis in selected patients when other effective treatments cannot be used. Severe lung disease or widespread infection requires intensive antifungal treatment under medical supervision.
Oral ketoconazole is used for histoplasmosis caused by Histoplasma capsulatum in selected patients when other effective treatments are not available or cannot be tolerated. The choice of treatment depends on how severe the infection is, the person's immune status, and clinical response.
Oral ketoconazole may be used to treat paracoccidioidomycosis (South American blastomycosis) caused by Paracoccidioides spp., particularly when other antifungal treatment options are unavailable or not well tolerated in Australia.
Take ketoconazole tablets exactly as prescribed by your doctor or other health professional.
The usual starting dose for adults in Australian product information is 200 mg once daily. In severe infections, or if the expected clinical response is not achieved, the dose may be increased to 400 mg once daily according to clinical response and tolerability.
Use in children: ketoconazole tablets have not been systematically studied in children. Use in paediatric patients is generally avoided unless a specialist decides that the potential benefit outweighs the risks.
Ketoconazole needs stomach acid to be absorbed properly. Medicines that reduce stomach acid, such as antacids, H2-blockers and proton pump inhibitors, may reduce absorption. If you take acid-reducing medicines or have low stomach acid, ask your prescriber or pharmacist how to take ketoconazole and how far apart to space your doses.
Ketoconazole tablets can cause serious side effects, including severe liver injury, which may be fatal or require a liver transplant, adrenal insufficiency, and QT prolongation (serious heart rhythm problems). In Australia, your healthcare provider may order blood tests to check liver function before and during treatment.
Stop taking ketoconazole tablets and get medical help straight away if you develop symptoms of liver injury, such as loss of appetite, nausea/vomiting, unusual tiredness, stomach pain, dark urine, light-coloured stools, yellowing of the skin or eyes, fever, or rash.
Tell your healthcare provider if you have liver problems now or have had them in the past, heart rhythm problems, adrenal problems, or if you take multiple medicines, including over-the-counter products and supplements. Avoid alcohol while taking ketoconazole tablets.
Ketoconazole tablets are contraindicated in patients with known hypersensitivity to ketoconazole.
Because ketoconazole can prolong the QT interval and cause serious drug interactions, taking it with certain medicines is contraindicated. Examples listed in official product information include: dofetilide, quinidine, pimozide, cisapride, methadone, disopyramide, dronedarone, and ranolazine (and in some labelling, lurasidone), due to the risk of life-threatening ventricular dysrhythmias such as torsades de pointes.
Taking ketoconazole with certain benzodiazepines, such as oral midazolam or triazolam, is contraindicated because ketoconazole can markedly increase their levels and effects.
Pregnancy: Tell your healthcare provider if you are pregnant or plan to become pregnant. It is not known whether ketoconazole tablets will harm your unborn baby.
Breastfeeding: Ketoconazole can pass into breast milk. You and your healthcare provider should decide whether you will take ketoconazole tablets or breastfeed. You should not do both.
Side effects may include nausea, abdominal discomfort, diarrhoea, headache, dizziness, and abnormal liver function test results. Ketoconazole can interfere with steroid biosynthesis and may cause hormone-related side effects, such as gynecomastia, menstrual irregularities, decreased libido, or adrenal suppression, especially at higher doses.
Ketoconazole is a strong inhibitor of CYP3A4 and has many clinically significant drug interactions. Some combinations are contraindicated because of the risk of serious heart rhythm problems (QT prolongation), excessive sedation, or other severe side effects.
Drug classes that may interact include medicines that affect heart rhythm, certain sedatives, some cholesterol-lowering medicines, immunosuppressants, anticoagulants, and many others. Tell your healthcare provider and Australian pharmacist about all prescription and over-the-counter medicines, vitamins, and herbal supplements you take before starting ketoconazole.
Medicines that affect stomach acid, including antacids, H2-blockers, proton pump inhibitors, and sucralfate, may reduce ketoconazole absorption. Ask a pharmacist about spacing doses if these medicines are needed.
If you miss a dose, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses at the same time.
In case of overdose, get emergency medical help or contact a Poisons Information Centre. Treatment is supportive.
Ketoconazole tablets should be protected from moisture and stored in well-closed containers at 15-25°C (59-77°F). Keep out of reach of children.
I'm in Wollongong. Can I enter my postcode before ordering to check whether these ketoconazole tablets can be delivered to me?
Yes. Enter your Wollongong postcode at checkout to see the delivery options available for your address. Availability is confirmed there before you place the order.
I'm about to start ketoconazole tablets for a fungal infection. Which side effects would mean I need urgent medical advice?
Seek urgent medical advice for yellowing of the skin or eyes, dark urine, pale stools, persistent nausea or vomiting, unusual tiredness, loss of appetite or upper abdominal pain, as these can indicate liver injury. Do not take another dose until a clinician has advised you if these symptoms occur.
| Active ingredient | Ketoconazole |
|---|---|
| Drug class | Azole antifungal |
| Dosage form | Tablet |
| Available strengths | 200 mg |
| Route | Oral |
| Storage | Store at 20°C to 25°C; excursions permitted between 15°C and 30°C. Protect from moisture and light. |
| ATC code | J02AB02 |
This product has 28 ratings, but only 4 written reviews so far. Share your experience and help other customers.
The outer packaging was neutral. Nothing on it advertised the contents.
About storing the unopened package, support answered my question clearly.
When I checked the package on arrival, the inner packaging of the order for ketoconazole was secure, and the medicine was undamaged.
I'm happy with this generic.
